Send to

Choose Destination
See comment in PubMed Commons below
Trends Neurosci. 2001 Apr;24(4):216-8.

RNAi and brain function: was McConnell on the right track?

Author information

UIC Psychiatric Institute, University of Illinois at Chicago MC912, 1601 W. Taylor Street, Chicago, IL 60612, USA.


RNA interference (RNAi), one of the hottest topics of molecular biology research today, has unique features that are eerily reminiscent of the phenomenon of "RNA-mediated memory transfer," a controversial line of work that was investigated with great enthusiasm in the 1960s. If not a coincidence, then this suggests taking a new look at RNA-mediated modulation of neural function and raises the possibility that RNAi might be one of the physiologic mechanisms that regulate long-term gene expression in the brain.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center