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Am J Cardiol. 2001 Mar 15;87(6):805-7, A9.

Plasma levels of vascular endothelial growth factor and its soluble receptor (SFlt-1) in essential hypertension.

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1
University Department of Medicine, City Hospital, Birmingham, United Kingdom.

Abstract

In this study of 27 untreated patients with uncomplicated essential hypertension, we report on elevated plasma levels of vascular endothelial growth factor and its soluble receptor Flt-1 compared with healthy controls; these increased levels are reduced by the treatment of hypertension. This raises the possibility that abnormal angiogenesis may contribute to the pathogenesis of complications related to hypertension and merits exploration in larger studies.

PMID:
11249912
DOI:
10.1016/s0002-9149(00)01512-5
[Indexed for MEDLINE]

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