Format

Send to

Choose Destination
J Neurosci Methods. 2001 Mar 30;106(1):69-79.

Multiple microelectrode-recording system for human intracortical applications.

Author information

1
Institute for Psychology of the Hungarian Academy of Sciences, Budapest, Hungary. Ulbert@cogpsyphy.hu

Abstract

The human brain is dominated by the neocortex, a large folded surface, whose cellular and synaptic elements are arranged in layers. Since cortical structure is relatively constant across its surface, local information processing can be inferred from multiple laminar recordings of its electrical activity along a line perpendicular to its surface. Such recordings need to be spaced at least as close together as the cortical layers, and need to be wideband in order to sample both low frequency synaptic currents as well as high-frequency action potentials. Finally, any device used in the human brain must comply with strict safety standards. The current paper presents details of a system meeting these criteria, together with sample results obtained from epileptic subjects undergoing acute or chronic intracranial monitoring for definition of the epileptogenic region.

PMID:
11248342
DOI:
10.1016/s0165-0270(01)00330-2
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center