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FEBS Lett. 2001 Mar 9;492(1-2):4-8.

Pathophysiological relevance of mitochondria in NAD(+) metabolism.

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1
Dipartment de Chimica Biologica, Università di Padova, Italy. dilisa@civ.bio.unipd.it

Abstract

Pyridine nucleotides are mostly stored within mitochondria where they are involved in different functions ranging from energy metabolism to cellular signaling. Here we discuss the mechanisms of mitochondrial NAD(+) metabolism and release that may contribute to the crucial roles played by these organelles as triggers or amplifiers of physiological and pathological events.

PMID:
11248227
[Indexed for MEDLINE]
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