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Curr Opin Neurobiol. 2000 Dec;10(6):683-90.

The role of short-term synaptic dynamics in motor control.

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Department of Mathematical Sciences, New Jersey Institute of Technology, Rutgers University, University Heights Newark, Newark, NJ 07102, USA.


During the past few years, much attention has been given to the role of short-term synaptic plasticity, in particular depression and facilitation, in sculpting network activity. A recent study shows that synaptic depression in rhythmic motor networks could switch the control of network frequency from intrinsic neuronal properties to the synaptic dynamics. Short-term synaptic plasticity is also involved in the stabilization and reconfiguration of motor circuits and in the initiation, maintenance and modulation of motor programs.

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