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Curr Biol. 2001 Feb 6;11(3):R88-91.

mRNA quality control: Marking the message for life or death.

Author information

1
Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, 295 Congress Avenue, New Haven, CT 06536, USA. jl346@email.med.yale.edu

Abstract

A protein complex deposited upstream of exon-exon junctions after pre-mRNA splicing may serve a dual role in mRNA quality control by directing mRNA nuclear export and, possibly, serving as a downstream 'mark' for nonsense-mediated decay.

PMID:
11231165
DOI:
10.1016/s0960-9822(01)00036-7
[Indexed for MEDLINE]
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