Send to

Choose Destination
Curr Biol. 2001 Jan 23;11(2):R49-52.

Clathrin uncoating: Auxilin comes to life.

Author information

Department of Molecular Biology and Microbiology, Case Western Reserve, University School of Medicine, 10900 Euclid Avenue, Cleveland, Ohio 44106-4960, USA.


The DnaJ protein auxilin has been extensively studied in vitro as a cofactor for uncoating clathrin-coated vesicles by the chaperone Hsc70. Recent studies provide the first evidence that auxilin plays this role in vivo, and work on a new mammalian auxilin suggests the protein may have more complex cellular functions.

[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center