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Curr Opin Immunol. 2001 Apr;13(2):195-201.

B1 cells: similarities and differences with other B cell subsets.

Author information

1
Division of Developmental and Clinical Immunology, Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294-3300, USA.

Abstract

Since their discovery, B1 B cells' origins and developmental pathways have eluded characterization. In the past year, focus on B1 B cells has shifted dramatically from developmental to functional aspects of these cells. Most advances have been made in describing the physiological activities of B1 cells, including their migration, activation by antigen and role in both autoimmunity and malignancy.

PMID:
11228413
DOI:
10.1016/s0952-7915(00)00204-1
[Indexed for MEDLINE]

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