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Nucleic Acids Res. 2001 Mar 1;29(5):1185-90.

GeneSplicer: a new computational method for splice site prediction.

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1
The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA.

Abstract

GeneSplicer is a new, flexible system for detecting splice sites in the genomic DNA of various eukaryotes. The system has been tested successfully using DNA from two reference organisms: the model plant Arabidopsis thaliana and human. It was compared to six programs representing the leading splice site detectors for each of these species: NetPlantGene, NetGene2, HSPL, NNSplice, GENIO and SpliceView. In each case GeneSplicer performed comparably to the best alternative, in terms of both accuracy and computational efficiency.

PMID:
11222768
PMCID:
PMC29713
[Indexed for MEDLINE]
Free PMC Article
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