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Bioinformatics. 2001 Jan;17(1):83-94.

ISYS: a decentralized, component-based approach to the integration of heterogeneous bioinformatics resources.

Author information

1
National Center for Genome Resources, 2935 Rodeo Park Drive East, Santa Fe, NM 87505, USA. isys@ncgr.org

Abstract

MOTIVATION:

Heterogeneity of databases and software resources continues to hamper the integration of biological information. Top-down solutions are not feasible for the full-scale problem of integration across biological species and data types. Bottom-up solutions so far have not integrated, in a maximally flexible way, dynamic and interactive graphical-user-interface components with data repositories and analysis tools.

RESULTS:

We present a component-based approach that relies on a generalized platform for component integration. The platform enables independently-developed components to synchronize their behavior and exchange services, without direct knowledge of one another. An interface-based data model allows the exchange of information with minimal component interdependency. From these interactions an integrated system results, which we call ISYSf1.gif" BORDER="0">. By allowing services to be discovered dynamically based on selected objects, ISYS encourages a kind of exploratory navigation that we believe to be well-suited for applications in genomic research.

PMID:
11222265
DOI:
10.1093/bioinformatics/17.1.83
[Indexed for MEDLINE]

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