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Eur J Surg. 2001 Jan;167(1):15-8.

Advanced breast biopsy instrumentation for the evaluation of impalpable lesions: a reliable diagnostic tool with little therapeutic potential.

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1
Department of Surgery, University of Basel, Switzerland.

Abstract

OBJECTIVE:

To assess the potential of advanced breast biopsy instrumentation (ABBI) to clarify the diagnosis of impalpable mammographic lesions and to remove the entire malignant lesions with clear margins.

DESIGN:

Prospective assessment in a consecutive series of patients.

SETTING:

University hospital, Basel, Switzerland.

SUBJECTS:

139 patients presenting with 144 impalpable microcalcifications or solid nodular densities evident on screening and follow-up mammograms that were suspicious of malignancy.

MAIN OUTCOME MEASURES:

Feasibility, sensitivity, efficiency in obtaining definitive diagnoses in an outpatient clinic under local anaesthesia, feasibility of complete removal of a primary malignancy, and intervention-related morbidity.

RESULTS:

The ABBI procedure was successful in 135/144 (94%); an accurate diagnosis was made in 129/130 patients followed up (99%), sensitivity for malignant lesions was 31/32 (97%) and there were 2 complications (2%). Margins of the biopsy cylinder contained a malignant lesion in 26/31 (84%).

CONCLUSIONS:

Excisional biopsy using the ABBI system is a reliable diagnostic tool with a low morbidity. As in other published series margins were often not clear of tumour and therefore the therapeutic use of the ABBI procedure is limited.

PMID:
11213814
DOI:
10.1080/110241501750069756
[Indexed for MEDLINE]
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