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Lancet. 2001 Jan 20;357(9251):195-6.

Efficacy of meningococcal serogroup C conjugate vaccine in teenagers and toddlers in England.


The UK was the first country to use meningococcal serogroup C conjugate (MCC) vaccines, which were licensed on the basis of immunogenicity and safety data but without a formal efficacy study. Increased surveillance during the first 9 months since introduction has shown that short-term efficacy of the MCC vaccine in England was 97% (95% CI 77-99) for teenagers and 92% (65-98) for toddlers. These early results confirm the superiority of MCC over plain C polysaccharide vaccines, which are ineffective in young children.

[Indexed for MEDLINE]

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