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Bioorg Med Chem Lett. 2001 Feb 12;11(3):295-9.

General synthesis of alpha-substituted 3-bisaryloxy propionic acid derivatives as specific MMP inhibitors.

Author information

1
Institut de Recherches Servier, Croissy sur Seine, France.

Abstract

Modulations of alpha and aryl substitutions on 3-aryloxy propionic acid hydroxamates led to novel and potent inhibitors of MMP-2,3,9 and 13, and selectivity versus MMP-1.

PMID:
11212095
DOI:
10.1016/s0960-894x(00)00646-6
[Indexed for MEDLINE]

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