Abstract
Although the role of androgens and AR in breast cancer genesis, development of breast cancer and tumor responsiveness to endocrine therapies is poorly understood, the widespread expression of AR suggests that it may be of biological and clinical importance in human breast cancer.
Publication types
-
Research Support, Non-U.S. Gov't
-
Review
MeSH terms
-
Adrenal Glands / metabolism
-
Androgens / metabolism*
-
Breast Neoplasms / etiology*
-
Breast Neoplasms / genetics
-
Breast Neoplasms / metabolism*
-
Female
-
Humans
-
Ligands
-
Menopause / metabolism
-
Menstrual Cycle / metabolism
-
Models, Biological
-
Neoplasms, Hormone-Dependent / etiology*
-
Neoplasms, Hormone-Dependent / genetics
-
Neoplasms, Hormone-Dependent / metabolism*
-
Ovary / metabolism
-
Receptors, Androgen / genetics
-
Receptors, Androgen / metabolism*
-
Transcription Factors / metabolism
Substances
-
Androgens
-
Ligands
-
Receptors, Androgen
-
Transcription Factors