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Pediatr Int. 2001 Feb;43(1):71-3.

Endomysium antibodies in the diagnosis of celiac disease in short-statured children with no gastrointestinal symptoms.

Author information

1
Department of Pediatrics, Gazi University, School of Medicine, Ankara, Turkey. tumer@marketweb.net.tr

Abstract

BACKGROUND:

Endomysium antibodies (EmAb) are strongly associated with untreated celiac disease and are suggested to be diagnostic. The aim of the present study was to assess the value of anti-EmAb for celiac disease screening in children with short stature.

METHODS:

In 84 children with height less than the third percentile for age, preliminary work-ups were made to find a cause for their short stature and then their serum was assayed for anti-EmAb by indirect immunofluorescence tests using monkey esophagus.

RESULTS:

Seven children were strongly positive for EmAb and all had positive histologic findings for celiac disease.

CONCLUSIONS:

Our results show that there is an association with occult celiac disease and idiopathic short stature and that the serum anti-EmAb test is useful in identifying such cases.

PMID:
11208004
[Indexed for MEDLINE]

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