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Ann N Y Acad Sci. 2000;923:43-58.

Clara cell proteins.

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Department of Veterans Affairs and Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15240, USA.


Clara cells are nonciliated, nonmucous, secretory cells of the pulmonary airways. These cells are known to secrete a variety of proteins, including Clara cell 10-kDa protein/uteroglobin. This protein consists of a homodimer of 70-77 amino acid polypeptides arranged in antiparallel fashion. In vitro testing suggests that the protein suppresses inflammation. The physiologic role of the protein remains to be determined.

[Indexed for MEDLINE]

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