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Ann N Y Acad Sci. 2000;923:43-58.

Clara cell proteins.

Author information

1
Department of Veterans Affairs and Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15240, USA. gurmukh@pol.net

Abstract

Clara cells are nonciliated, nonmucous, secretory cells of the pulmonary airways. These cells are known to secrete a variety of proteins, including Clara cell 10-kDa protein/uteroglobin. This protein consists of a homodimer of 70-77 amino acid polypeptides arranged in antiparallel fashion. In vitro testing suggests that the protein suppresses inflammation. The physiologic role of the protein remains to be determined.

[Indexed for MEDLINE]

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