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MMWR Morb Mortal Wkly Rep. 2000 Dec 22;49(50):1138-40.

Availability and use of parenteral quinidine gluconate for severe or complicated malaria.


Since 1991, quinidine gluconate, a class 1a anti-arrhythmic agent, has been the only parenteral antimalarial available for use in the United States (1). It is indicated for the treatment of patients with life-threatening Plasmodium falciparum malaria (2), including those who cannot tolerate oral therapy, have high-grade parasitemia, or have complications (e.g., cerebral malaria or acute renal failure).

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