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Trends Neurosci. 2001 Mar;24(3):155-62.

Generating diversity at GABAergic synapses.

Author information

1
Biophysics Sector, International School of Advanced Studies, I-34014 Trieste, Italy.

Abstract

GABA-mediated transmission is characterized by high variability of synaptic responses. Major contributors to this variability are: presynaptic factors, including release probability and number of release sites; factors that determine synaptic GABA transients in the cleft, including diffusion and the actions of GABA transporters; and postsynaptic factors, including GABA(A) receptors subtypes, their location and number, their modulation by endogenous and exogenous factors, and their interactions with postsynaptic-anchoring proteins.

PMID:
11182455
DOI:
10.1016/s0166-2236(00)01724-0
[Indexed for MEDLINE]

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