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Curr Opin Neurobiol. 2001 Feb;11(1):118-26.

Dendritic arbor development and synaptogenesis.

Author information

1
Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724, USA. Cline@cshl.org

Abstract

In vivo studies indicate that synaptic activity promotes dendritic arbor elaboration at early stages of brain development. At later stages of development, synaptic activity stabilizes dendritic structure. The different roles of synaptic activity with respect to structural plasticity probably reflect the regulated spatiotemporal expression of key components within signaling pathways.

PMID:
11179881
DOI:
10.1016/s0959-4388(00)00182-3
[Indexed for MEDLINE]

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