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Bull Exp Biol Med. 2000 Sep;130(9):846-8.

Antiamnesic effect of acyl-prolyl-containing dipeptide (GVS-111) in compression-induced damage to frontal cortex.

Author information

1
Institute of General Pathology and Pathophysiology; Institute of Pharmacology; Brain Research Institute, Russian Academy of Medical Sciences, Moscow.parochial@mtu-net.ru

Abstract

Antiamnestic effect of acyl-prolyl-containing dipeptide GVS-111 was demonstrated in rats with bilateral compression-induced damage to the frontal cortex. Both intraperitoneal and oral administration of the dipeptide improved retrieval of passive avoidance responses in rats with compression-induced cerebral ischemia compared to untreated controls.

PMID:
11177261
[Indexed for MEDLINE]

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