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Nat Genet. 2001 Feb;27(2):136-7.

Modifying with mitochondria.

Author information

1
Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. karena@post.tau.ac.il

Abstract

An elegant set of mouse crosses has been used to identify a mitochondrial variant that interacts with a nuclear locus on chromosome 10, Ahl, to modify age-related hearing loss. This discovery sets the stage for the identification of factors that modify expression levels and variability of human hearing impairments.

PMID:
11175774
DOI:
10.1038/84743
[Indexed for MEDLINE]

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