Surfactant protein-A gene locus associated with recurrent otitis media

M Rämet; J Löfgren; O P Alho; M Hallman

doi:10.1067/mpd.2001.110133

Surfactant protein-A gene locus associated with recurrent otitis media

J Pediatr. 2001 Feb;138(2):266-8. doi: 10.1067/mpd.2001.110133.

Authors

M Rämet¹, J Löfgren, O P Alho, M Hallman

Affiliation

¹ Department of Pediatrics, University Central Hospital, and Biocenter Oulu, University of Oulu, Oulu, Finland.

PMID: 11174628
DOI: 10.1067/mpd.2001.110133

Abstract

Surfactant protein-A, which plays a role in innate host defense in the lung, is also expressed in the Eustachian tube. We report that the frequency of specific surfactant protein-A haplotypes and genotypes differs between children with recurrent otitis media compared with a control population.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Child
Child, Preschool
Chromosome Mapping
Female
Genetic Predisposition to Disease
Humans
Infant
Lectins / genetics*
Male
Otitis Media / genetics*
Proteolipids / genetics*
Pulmonary Surfactant-Associated Proteins
Pulmonary Surfactants / genetics*
Recurrence

Substances

Lectins
Proteolipids
Pulmonary Surfactant-Associated Proteins
Pulmonary Surfactants