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Cardiology. 2000;94(2):127-8.

Rhabdomyolysis and acute renal failure after changing statin-fibrate combinations.

Author information

1
Department of Internal Medicine, Creighton University, Omaha, NE, USA.

Abstract

Statin-fibrate combinations are commonly used to treat hyperlipidemia. These drugs have been previously reported to cause rhabdomyolysis with acute renal failure. Whether different statin-fibrate combinations have different risks for rhabdomyolysis is not known. We report a patient who developed rhabdomyolysis with acute renal failure promptly after switching from the combination of pravastatin and fenofibrate to simvastatin and gemfibrozil.

PMID:
11173785
DOI:
10.1159/000047304
[Indexed for MEDLINE]

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