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Ann Dermatol Venereol. 2000 Dec;127(12):1087-9.

[Subcutaneous fat necrosis of the newborn with hypercalcemia].

[Article in French]

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Service de Dermatologie, CHU Besançon, 2, place Saint-Jacques, 25030 Besançon Cedex.



Hypercalcemia associated with subcutaneous fat necrosis of the newborn is a well known but rare event.


A newborn with a history of cesarean section, fetomaternal infection, neurological and respiratory distress was admitted with anorexia, adynamia, vomiting, polyuria and polydipsia at the age of 37 days. Physical examination showed red and violaceous infiltrated skin lesions. Skin biopsy revealed focal areas of fat necrosis with crystal-like structures. Calcium and 1,25 (OH(2) ) vitamin D serum levels were increased. Diagnostic of subcutaneous fat necrosis of the newborn with symptomatic hypercalcemia was made. Evolution was favorable after treatment including furosemide, prednisone and a diet low in calcium and vitamin D.


Hypercalcemia must be detected in infants with subcutaneous fat necrosis. This major complication may have fatal outcome. Treatment of hypercalcemia includes dietary changes associated with classic treatment of hypercalcemia. Routine evaluation of serum calcium level is essential.

[Indexed for MEDLINE]

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