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Curr Opin Microbiol. 2001 Feb;4(1):82-9.

Bordetella pertussis, molecular pathogenesis under multiple aspects.

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INSERM U447, Institut Pasteur de Lille, 1 rue du Prof. Calmette, F-59019, Lille Cedex, France.


Recent studies, including those based on genomics, have demonstrated that besides toxins and adhesins, Bordetella pertussis uses many additional virulence determinants. Most of them are part of the BvgAS regulon, although some, in particular iron-uptake systems, are independent of BvgAS. They are regulated by iron, although in one case, the production of a siderophore receptor could be linked to the BvgAS regulon.

[Indexed for MEDLINE]

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