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Chest. 2001 Feb;119(2 Suppl):419S-425S.

Novel nonantibiotic therapies for pneumonia: cytokines and host defense.

Author information

1
Louisiana State University Health Sciences Center, Department of Medicine, 1901 Perdido St., New Orleans, LA 70112, USA. snelso1@lsuhsc.edu

Abstract

Effective host defense against bacterial infection is dependent on the activation and recruitment of phagocytic cells. The initiation, maintenance, and resolution of this inflammatory response in the setting of bacterial pneumonia is dependent on the expression of cytokines. As the complexities of the host-pathogen interaction are further dissected and unraveled, immunologic manipulation of cytokine expression will likely become an important adjuvant therapy in the treatment of serious lung infections.

PMID:
11171779
DOI:
10.1378/chest.119.2_suppl.419s
[Indexed for MEDLINE]

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