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Biochem Soc Trans. 2000 Dec;28(6):796-8.

The non-mevalonate isoprenoid biosynthesis of plants as a test system for drugs against malaria and pathogenic bacteria.

Author information

1
Botanical Institute II, University of Karlsruhe, Kaiserstr. 12, D-76128 Karlsruhe, Germany.

Abstract

Two plant test systems are presented in the search for new inhibitors of the non-mevalonate isoprenoid pathway. A derivative of clomazone appears to be an inhibitor of the deoxyxylulose 5-phosphate/methylerythritol 4-phosphate (DOXP/MEP) pathway of isoprenoid formation.

PMID:
11171212
[Indexed for MEDLINE]

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