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Clin Infect Dis. 2001 Jan 15;32(2):307-10. Epub 2000 Dec 22.

Immunogenicity of pneumococcal vaccine in heart transplant recipients.

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  • 1Department of Medicine and MCP Hahnemann School of Medicine, Philadelphia, PA, USA. blumbere@mail.med.upenn.edu

Abstract

To assess the immunogenicity of pneumococcal vaccine in recipients of heart transplants, we immunized 35 long-term transplantation survivors with pneumococcal vaccine and measured the pre- and postvaccination IgG antibody titers to 5 representative vaccine capsular polysaccharides. Responses of heart transplant recipients to pneumococcal vaccine antigens were generally suppressed.

PMID:
11170924
DOI:
10.1086/318482
[PubMed - indexed for MEDLINE]
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