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Trends Biochem Sci. 2001 Feb;26(2):118-24.

The complexities of dystroglycan.

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Institute of Biomedical and Life Sciences, Division of Biochemistry and Molecular Biology, Davidson Building, University of Glasgow, G12 8QQ, Glasgow, UK.

Erratum in

  • Trends Biochem Sci 2001 Sep;26(9):575.


The notion of dystroglycan as a simple laminin-binding receptor is increasingly being challenged. New roles and new binding partners are continually emerging. Recent structural advances have provided exciting new insights into the precise molecular interactions between dystroglycan and other key components of the dystroglycan complex. Coupled with an increasing understanding of dystroglycan function at the molecular level, we are finally beginning to probe the complexities of dystroglycan, not only in disease, but in development, adhesion and signalling.

[Indexed for MEDLINE]

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