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Curr Opin Genet Dev. 2001 Feb;11(1):91-7.

Coordinating cell proliferation and differentiation.

Author information

1
Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York 10461, USA. lizhu@aecom.yu.edu

Abstract

Cell proliferation and differentiation are highly coordinated processes during development. Recent studies have revealed that this coordination may result from dual functions residing in the central regulators of proliferation, allowing them to also regulate differentiation. Studies have also shown that some terminally differentiated cells can be made to divide beyond their normal capacity.

PMID:
11163157
DOI:
10.1016/s0959-437x(00)00162-3
[Indexed for MEDLINE]

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