Format

Send to

Choose Destination
Exp Gerontol. 2001 Jan;36(1):21-8.

Prolonged longevity of hypopituitary dwarf mice.

Author information

1
Department of Physiology, Southern Illinois University School of Medicine, Carbondale, IL 62901-6512, USA. abartke@som.siu.edu

Abstract

In two types of mutant dwarf mice, congenital deficiencies in pituitary function are associated with remarkably increased life expectancy. In this review, we will describe the key phenotypic characteristics of these animals, the evidence that they exhibit delayed aging, and the mechanisms that are suspected to account for their prolonged longevity.

PMID:
11162909
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center