Format

Send to

Choose Destination
See comment in PubMed Commons below
Semin Cell Dev Biol. 2001 Feb;12(1):53-8.

Calcium and mitosis.

Author information

1
Department of Physiological Sciences, Medical School, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK. michael.whitaker@ncl.ac.uk

Abstract

Calcium is thought to be involved in regulating mitotic transitions. The basis for this view is set out. Recent data from experiments on sea urchin embryos is discussed. The relative simplicity of the embryonic cell cycle and the relative ease with which cell physiology can be done in sea urchin embryos has allowed the clear demonstration that the phosphoinositide-calcium-calmodulin signalling pathway is required for and regulates mitosis entry and anaphase onset. The relevance of the sea urchin work to mitosis in other cell types is briefly discussed.

PMID:
11162747
DOI:
10.1006/scdb.2000.0217
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center