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Semin Cell Dev Biol. 2001 Feb;12(1):11-7.

ER calcium and the functions of intracellular organelles.

Author information

1
Medical Research Council Secretory Control Research Group, The Physiological Laboratory, The University of Liverpool, Crown Street, Liverpool, L69 3BX, P.O. Box 147, UK.

Abstract

Cytosolic calcium has long been known as a second messenger of major significance. Recently it has become apparent that calcium stored in cellular organelles can also be an important regulator of cellular functions. The endoplasmic reticulum (ER) is usually the largest store of releasable calcium in the cell. The diverse signalling functions of calcium populating the endoplasmic reticulum and its interactions with other organelles are illustrated in Figure ?? and described in this paper.

PMID:
11162742
DOI:
10.1006/scdb.2000.0212
[Indexed for MEDLINE]

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