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Chest. 2001 Jan;119(1):70-6.

Gender moderates the effects of exercise therapy on health-related quality of life among COPD patients.

Author information

1
Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC, USA.

Abstract

STUDY OBJECTIVES:

To determine whether long-term treatment with exercise therapy results in more favorable, disease-specific, health-related quality of life (HRQL) compared with short-term treatment with exercise therapy; and to determine whether there are gender differences in disease-specific HRQL among individuals randomized into the two treatment groups.

DESIGN:

Randomized clinical trial.

SETTING:

Center-based exercise therapy unit at a university.

PARTICIPANTS:

One hundred forty patients with COPD; 118 completed trial.

INTERVENTIONS:

Short-term exercise therapy (3 months); long-term exercise therapy (18 months).

MEASUREMENTS:

Chronic Disease Respiratory Questionnaire (CRQ).

RESULTS:

After 3 months of treatment, there were significant improvements in all CRQ scores for men and women (p < 0.01), and for the total sample (p < 0.01). At 18 months, individuals randomized into the long-term group had significantly more favorable scores than the short-term group for dyspnea (p = 0.03), fatigue (p < 0.01), emotional function (p = 0.04), and mastery (p = 0.04). However, these effects were moderated by gender. That is, men in the long-term group reported significantly more favorable scores than men in the short-term group for dyspnea (0.04), fatigue (p < 0.001), emotional function (p = 0.02), and mastery (p = 0.02). At the 18-month assessment, there were no differences between long-term and short-term exercise therapy for women on any of the subscales of the CRQ.

CONCLUSIONS:

Taken collectively, the CRQ data demonstrate that long-term exercise therapy has little added benefit for women over short-term exercise therapy; however, men derive significant benefits from extended training.

PMID:
11157586
DOI:
10.1378/chest.119.1.70
[Indexed for MEDLINE]

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