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Neurology. 2001 Jan 9;56(1):97-9.

Mycophenolate mofetil for myasthenia gravis: an open-label pilot study.

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  • 1Division of Neurology, Duke University Medical Center, Durham, NC, USA.


In an open-label study, 12 patients with refractory MG or who were taking only corticosteroids and required additional immunosuppression received mycophenolate mofetil 1 g twice daily for 6 months. A reduction of three points in a quantified MG score and two points in a manual muscle test or a reduction of 50% in corticosteroid dose defined efficacy. Eight patients improved, beginning after 2 weeks to 2 months. No major side effects were observed.

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