Abstract
Recent work has revealed an evolutionarily conserved trio of proteins that regulate cell polarity in epithelial cells, embryonic blastomeres and neural precursors. This common cell-polarity mechanism is used in cell-specific ways, as highlighted by the recent finding that at least two different types of asymmetric division are observed in Drosophila neural precursors.
MeSH terms
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Animals
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Caenorhabditis elegans / cytology
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Caenorhabditis elegans / embryology
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Caenorhabditis elegans / genetics
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Caenorhabditis elegans Proteins*
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Carrier Proteins / genetics
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Carrier Proteins / metabolism
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Cell Division / genetics
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Cell Polarity / genetics*
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Drosophila / cytology
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Drosophila / embryology*
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Drosophila / genetics
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Drosophila Proteins*
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Epithelial Cells / cytology
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Epithelial Cells / metabolism
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Helminth Proteins / genetics
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Helminth Proteins / metabolism
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Intracellular Signaling Peptides and Proteins*
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Oocytes / cytology
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Oocytes / growth & development
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Oocytes / metabolism
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Protein Kinase C / genetics
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Protein Kinase C / metabolism
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Protein Serine-Threonine Kinases
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Proteins / genetics
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Proteins / metabolism
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Stem Cells / cytology
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Stem Cells / metabolism*
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Xenopus / embryology
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Xenopus / genetics
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Xenopus Proteins
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Zygote / cytology
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Zygote / growth & development
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Zygote / metabolism
Substances
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Caenorhabditis elegans Proteins
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Carrier Proteins
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Drosophila Proteins
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Helminth Proteins
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Intracellular Signaling Peptides and Proteins
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PARD6B protein, Xenopus
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Proteins
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Xenopus Proteins
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baz protein, Drosophila
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par-6 protein, C elegans
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PAR-3 protein, C elegans
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Protein Serine-Threonine Kinases
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PKC-3 protein
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Protein Kinase C