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Microbes Infect. 2000 Nov;2(14):1733-42.

Pathogenesis of neonatal Streptococcus agalactiae infections.

Author information

1
Institute of Medical Microbiology and National Reference Center for Streptococci, University Hospital Aachen, Pauwelsstr. 30, D-52057, Aachen, Germany. bspeller@imib.rwth-aachen.de

Abstract

Streptococcus agalactiae is an important human pathogen causing severe neonatal infections. During the course of infection, S. agalactiae colonizes and invades a number of different host compartments. Bacterial molecules including the polysaccharide capsule, the hemolysin, the C5a peptidase, the C-proteins, the hyaluronate lyase and a number of unknown bacterial components determine the interaction with host tissues. This review summarizes our current knowledge about these interactions.

PMID:
11137046
DOI:
10.1016/s1286-4579(00)01328-9
[Indexed for MEDLINE]

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