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Microbes Infect. 2000 Nov;2(14):1705-19.

Hijacking of apoptotic pathwaysby bacterial pathogens.

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Department of Microbiology and Immunology, University of Kentucky Chandler Medical Center, Lexington, KY 40536-0084, USA.


Increasing evidence indicates that apoptosis of the host cell may constitute a defense mechanism to confine the infection by bacterial pathogens. Certain pathogens have developed elegant mechanisms to modulate the fate of the host cell, which include induction or blockage of apoptosis. These studies will promote our understanding of the pathogenesis of infectious diseases and aid the development of means for therapeutic intervention.

[Indexed for MEDLINE]

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