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Nat Med. 2001 Jan;7(1):21-3.

Yersinia lead SUMO attack.

Author information

1
Microbial Pathogenesis Unit, Christian de Duve Institute of Cellular Pathology and Faculty of Medicine, Université de Louvain, 74 Av Hippocrate, B1200 Brussels, Belgium. cornelis@mipa.ucl.ac.be

Abstract

Little is known about the mechanism by which Yops, proteins that Yersinia inject into the cytosol of macrophage, cause downregulation of the inflammatory response and diseases such as the plague. Now it appears that Yops are the first bacterial member of a new family of ubiquitin-like proteases.

PMID:
11135606
DOI:
10.1038/83298
[Indexed for MEDLINE]

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