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Neurology. 2000 Dec 26;55(12):1904-5.

Induction of psychogenic nonepileptic seizures without placebo.

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Comprehensive Epilepsy Program, University of South Florida College of Medicine, Tampa, FL, USA.


The diagnosis of psychogenic nonepileptic seizures (PNES) can only be made with EEG-video monitoring. The authors describe a provocative technique without placebo. Patients with a clinical suspicion for PNES underwent an activation procedure using suggestion, hyperventilation, and photic stimulation. Of 19 inductions performed, 16 (84%) were successful in inducing the habitual episode. The authors' technique had a sensitivity comparable to those using placebo (e.g., saline injection), but does not have disadvantages.

[Indexed for MEDLINE]

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