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Scand J Rheumatol. 2000;29(6):352-7.

Drug consumption in the first years of rheumatoid arthritis in France, The Netherlands, and Norway. A longitudinal study in the early nineties.

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1
Rheumatology Unit, CHU Brabois, Nancy, France.

Abstract

OBJECTIVE:

To analyse drug consumption in the first years of rheumatoid arthritis (RA) in France, the Netherlands, and Norway, in a longitudinal study between 1991 and 1993.

PATIENTS AND METHODS:

The EURIDISS cohort followed up over three years included 695 RA subjects with less than 5 years disease duration. Clinical and biological parameters, drug consumption according to ATC classification, and use of local treatment were recorded.

RESULTS:

In the Netherlands consumption of second-line treatment occurred early on, and remained constant over time. In France, it was consumed by half of the subjects and decreased during follow-up (p<0.001). In Norway, 50% of the subjects were on second-line treatment at the outset. NSAIDs rather than corticoids were the most widely consumed. Patients underwent frequently local treatments with decrease frequency of infiltrations over time (p<0.001).

CONCLUSION:

Second-line treatments were used in the first years of disease development, following varying sequences in the different countries.

PMID:
11132203
[Indexed for MEDLINE]
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