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Lancet. 2000 Dec 9;356(9246):1981-2.

Ep-CAM overexpression in breast cancer as a predictor of survival.

Abstract

The epithelial glycoprotein Ep-CAM is overexpressed in colon cancer and breast cancer. We assessed the frequency and prognostic significance of Ep-CAM in tissue specimens from 205 patients with invasive breast cancer, by immunohistochemical staining with a monoclonal antibody specific for the Ep-CAM antigen. Ep-CAM overexpression was found in 35.6% of samples and was associated with poor disease-free and overall survival.

PMID:
11130529
DOI:
10.1016/S0140-6736(00)03312-2
[Indexed for MEDLINE]

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