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Bioorg Med Chem Lett. 2000 Dec 4;10(23):2687-90.

Phenylpropenamide derivatives as inhibitors of hepatitis B virus replication.

Author information

1
Avid Therapeutics, Inc., Philadelphia, PA 19104, USA. robert_perni@vpharm.com

Abstract

A non-nucleoside class of compounds that inhibits the replication of hepatitis B virus (HBV) in cell culture has been discovered. A series of substituted analogues of phenylpropenamide 6 has been prepared and evaluated in the HepAD38 cellular assay. Structure-activity relationships of this series are discussed.

PMID:
11128652
[Indexed for MEDLINE]

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