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Br J Gen Pract. 2000 Oct;50(459):817-20.

How effective are treatments other than antibiotics for acute sore throat?

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  • 1Centre for General Practice, Graduate School of Medicine, University of Queensland, Australia.

Abstract

To estimate the benefits of treatments other than antibiotics for acute sore throat, and the differences between non-antibiotic interventions and controls in patient-perceived pain of sore throat, a systematic review of controlled trials in Medline and the Cochrane Library was carried out. Sixty-six randomised controlled trials (with or without additional antibiotics) were identified and 17 met the selection criteria. Twenty-two non-antibiotic managements for sore throat were compared. Their efficacy relative to placebo ranged from no effect to 93%. Some non-antibiotic treatments may be more effective than antibiotics; however, publication bias may have exaggerated the benefits. These treatments should be investigated further with respect to efficacy, safety, and side-effects as potential firstline management options for acute sore throat.

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PMID:
11127175
PMCID:
PMC1313826
[PubMed - indexed for MEDLINE]
Free PMC Article
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