Send to

Choose Destination
Intensive Care Med. 2000 Oct;26(10):1512-4.

Is leukocytosis a predictor of mortality in severe pertussis infection?

Author information

Paediatric Intensive Care Unit, Great Ormond Street Hospital for Children NHS Trust, London, UK.


Bordetella pertussis causing severe respiratory failure in infants that is unresponsive to treatment is well described. Pulmonary hypertension is a prominent feature of such cases. In this series of 13 critically ill infants with B. pertussis, hyperleukocytosis ( > 100 x 10(9)/l) was an independent predictor of death. We suggest that such extreme leukocytosis may contribute to disease severity via the formation of aggregates in the pulmonary vasculature.

[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center