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Am J Ophthalmol. 2000 Dec;130(6):839-41.

Choroidal neovascular membranes: reproducibility of angiographic interpretation.

Author information

1
Vitreous and Retina Consultants, Lakeland, Florida 33805, USA.

Abstract

PURPOSE:

To determine interobserver agreement for classifying choroidal neovascular membranes in age-related macular degeneration.

METHODS:

Six fluorescein angiograms of choroidal neovascular membranes were interpreted by 21 retina specialists. Reliability was measured by percent agreement and kappa coefficient.

RESULTS:

Interobserver agreement of membrane types ranged from perfect concordance for a small, classic membrane to near-random classification for a complex pattern. Mean kappa coefficient was.64. Interobserver agreement of membrane size was most variable for intermediate size lesions (mean kappa coefficient =.40).

CONCLUSION:

Fluorescein angiographic interpretation of choroidal neovascular membrane type and size can vary considerably. Interobserver agreement is better for membrane type than for membrane size.

PMID:
11124312
DOI:
10.1016/s0002-9394(00)00605-x
[Indexed for MEDLINE]

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