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Biochim Biophys Acta. 2000 Dec 1;1494(3):282-5.

Alternative splicing of the human PTEN/MMAC1/TEP1 gene.

Author information

1
YCR Cancer Research Unit, Department of Biology, University of York, Heslington, York YO10 5DD, UK. rms5@york.ac.uk

Abstract

The human tumour suppressor gene PTEN/MMAC1/TEP1 encodes a lipid and protein phosphatase. Using RT-PCR, alternatively spliced forms of PTEN mRNA, encoding full-length PTEN and two forms of the protein truncated at the C-terminal end, were detected in normal human tissue. Cultured tumour and non-tumour cell lines show similar splicing patterns.

PMID:
11121587
DOI:
10.1016/s0167-4781(00)00210-4
[Indexed for MEDLINE]

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