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Antimicrob Agents Chemother. 2001 Jan;45(1):342-4.

Identification of an erm(A) erythromycin resistance methylase gene in Streptococcus pneumoniae isolated in Greece.

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  • 1Department of Pediatrics, General University Hospital, University of Patras, School of Medicine, Patras, Greece. syrogian@med.upatras.gr

Abstract

In a serotype 11A clone of erythromycin-resistant pneumococci isolated from young Greek carriers, we identified the nucleotide sequence of erm(A), a methylase gene previously described as erm(TR) in Streptococcus pyogenes. The erm(A) pneumococci were resistant to 14- and 15-member macrolides, inducibly resistant to clindamycin, and susceptible to streptogramin B. To our knowledge, this is the first identification of resistance to erythromycin in S. pneumoniae attributed solely to the carriage of the erm(A) gene.

PMID:
11120994
PMCID:
PMC90289
DOI:
10.1128/AAC.45.1.342-344.2001
[PubMed - indexed for MEDLINE]
Free PMC Article
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