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Clin Infect Dis. 2000 Oct;31 Suppl 5:S185-9.

Physiological rationale for suppression of fever.

Author information

1
Medical Care Clinical Center, Veterans Affairs Maryland Health Care System, and Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Philip.Mackowiak@med.va.gov

Abstract

Two critical assumptions are made when prescribing antipyretic therapy. One is that fever is, at least in part, noxious, and the other is that suppression of fever will reduce, if not eliminate, the noxious effects of fever. At present, neither assumption has been validated experimentally.

PMID:
11113022
DOI:
10.1086/317511
[Indexed for MEDLINE]

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