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Curr Biol. 2000 Nov 16;10(22):R823-5.

Microbial pathogenesis: lipid rafts as pathogen portals.

Author information

1
Biotechnology Laboratory and Department of Microbiology and Immunology, University of British Columbia, British Columbia V6T 1Z3, Vancouver, Canada.

Abstract

The route of initial entry influences how host cells respond to intracellular pathogens. Recent studies have demonstrated that a wide variety of pathogens target lipid microdomains in host cell membranes, known as lipid rafts, to enter host cells as an infectious strategy.

PMID:
11102822
DOI:
10.1016/s0960-9822(00)00788-0
[Indexed for MEDLINE]
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